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Temperature-sensitive Mutants of Respiratory Syncytial Virus

Four conditional-lethal temperature-sensitive mutants of RS virus were detected among the progeny of 454 plaques derived from virus grown in the presence of 10(−4)m 5-fluorouridine. These mutants were stable (reversion frequency, 10(−5.0) or less and failed to produce plaques at 38 or 39 C. Plaquing...

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Main Authors: Gharpure, Meera A., Wright, Peter F., Chanock, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: 1969
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC375786/
https://ncbi.nlm.nih.gov/pubmed/4890619
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