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X Inactivation and Progenitor Cancer Cells

In mammals, silencing of one of the two X chromosomes is necessary to achieve dosage compensation. The 17 kb non-coding RNA called Xist triggers X inactivation. Gene silencing by Xist can only be achieved in certain contexts such as in cells of the early embryo and in certain hematopoietic progenito...

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Autore principale: Agrelo, Ruben
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757410/
https://ncbi.nlm.nih.gov/pubmed/24212802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3022169
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