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The Role of Nrf2 and Cytoprotection in Regulating Chemotherapy Resistance of Human Leukemia Cells

The Nrf2 anti-oxidant response element (ARE) pathway plays an important role in regulating cellular anti-oxidants. Under normal cellular conditions Nrf2 can be described as an anti-tumor molecule due to its induction of cytoprotective genes which protect cells from electrophile and oxidative damage....

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Autors principals: Rushworth, Stuart A., MacEwan, David J.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757381/
https://ncbi.nlm.nih.gov/pubmed/24212776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3021605
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