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Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia

We previously suggested links between specific XPD mutations in the fetal genome and the risk of placental maldevelopment and preeclampsia, possibly due to impairment of Transcription Factor (TF)IIH-mediated functions in placenta. To identify the underlying mechanisms, we conducted the current integ...

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Detalhes bibliográficos
Main Authors: Moslehi, Roxana, Mills, James L., Signore, Caroline, Kumar, Anil, Ambroggio, Xavier, Dzutsev, Amiran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757356/
https://ncbi.nlm.nih.gov/pubmed/23989136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02407
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