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Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?

The common preference of cancers for lactic acid-generating metabolic energy pathways has led to proposals that their reprogrammed metabolism confers growth advantages such as decreased susceptibility to hypoxic stress. Recent observations, however, suggest that it generates a novel way for cancer s...

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Bibliographic Details
Main Authors: Choi, Stephen Yiu Chuen, Collins, Colin C, Gout, Peter W, Wang, Yuzhuo
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757307/
https://ncbi.nlm.nih.gov/pubmed/23729358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4218
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