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Notch Signaling in Osteocytes Differentially Regulates Cancellous and Cortical Bone Remodeling

Notch receptors play a role in skeletal development and homeostasis, and Notch activation in undifferentiated and mature osteoblasts causes osteopenia. In contrast, Notch activation in osteocytes increases bone mass, but the mechanisms involved and exact functions of Notch are not known. In this stu...

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Détails bibliographiques
Auteurs principaux: Canalis, Ernesto, Adams, Douglas J., Boskey, Adele, Parker, Kristen, Kranz, Lauren, Zanotti, Stefano
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757222/
https://ncbi.nlm.nih.gov/pubmed/23884415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470492
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