Physical and Functional Association of Lactate Dehydrogenase (LDH) with Skeletal Muscle Mitochondria

The intracellular lactate shuttle hypothesis posits that lactate generated in the cytosol is oxidized by mitochondrial lactate dehydrogenase (LDH) of the same cell. To examine whether skeletal muscle mitochondria oxidize lactate, mitochondrial respiratory oxygen flux (JO(2)) was measured during the...

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Bibliographic Details
Main Authors: Elustondo, Pia A., White, Adrienne E., Hughes, Meghan E., Brebner, Karen, Pavlov, Evgeny, Kane, Daniel A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757195/
https://ncbi.nlm.nih.gov/pubmed/23873936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476648
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