Lacto-N-biosidase Encoded by a Novel Gene of Bifidobacterium longum Subspecies longum Shows Unique Substrate Specificity and Requires a Designated Chaperone for Its Active Expression

Infant gut-associated bifidobacteria possess species-specific enzymatic sets to assimilate human milk oligosaccharides, and lacto-N-biosidase (LNBase) is a key enzyme that degrades lacto-N-tetraose (Galβ1–3GlcNAcβ1–3Galβ1–4Glc), the main component of human milk oligosaccharides, to lacto-N-biose I (...

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Detalhes bibliográficos
Main Authors: Sakurama, Haruko, Kiyohara, Masashi, Wada, Jun, Honda, Yuji, Yamaguchi, Masanori, Fukiya, Satoru, Yokota, Atsushi, Ashida, Hisashi, Kumagai, Hidehiko, Kitaoka, Motomitsu, Yamamoto, Kenji, Katayama, Takane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757183/
https://ncbi.nlm.nih.gov/pubmed/23843461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484733
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