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The antidepressant-like effect of inosine in the FST is associated with both adenosine A(1) and A(2A) receptors
Inosine is an endogenous purine nucleoside, which is formed during the breakdown of adenosine. The adenosinergic system was already described as capable of modulating mood in preclinical models; we now explored the effects of inosine in two predictive models of depression: the forced swim test (FST)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757140/ https://ncbi.nlm.nih.gov/pubmed/23613131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-013-9361-8 |
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