Direct Delivery of Functional Proteins and Enzymes to the Cytosol Using Nanoparticle-Stabilized Nanocapsules

Intracellular protein delivery is an important tool for both therapeutic and fundamental applications. Effective protein delivery faces two major challenges: efficient cellular uptake and avoiding endosomal sequestration. We report here a general strategy for direct delivery of functional proteins t...

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Autors principals: Tang, Rui, Kim, Chang Soo, Solfiell, David J., Rana, Subinoy, Mout, Rubul, Velázquez-Delgado, Elih M., Chompoosor, Apiwat, Jeong, Youngdo, Yan, Bo, Zhu, Zheng-Jiang, Kim, Chaekyu, Hardy, Jeanne A., Rotello, Vincent M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757120/
https://ncbi.nlm.nih.gov/pubmed/23815280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn402753y
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