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Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys

In contrast to pathogenic HIV/SIV infections of humans and rhesus macaques (RMs), natural SIV infection of sooty mangabeys (SMs) is typically non-pathogenic despite high viremia. Several studies suggested that low immune activation and relative resistance of CD4+ central memory T-cells from virus in...

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Detalhes bibliográficos
Main Authors: Bosinger, Steven E., Johnson, Zachary P., Folkner, Kathryn A., Patel, Nirav, Hashempour, Tayebeh, Jochems, Simon P., del Rio Estrada, Perla M., Paiardini, Mirko, Lin, Rongtuan, Vanderford, Thomas H., Hiscott, John, Silvestri, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757038/
https://ncbi.nlm.nih.gov/pubmed/24009514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003597
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