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The Flavonoid Apigenin Downregulates CDK1 by Directly Targeting Ribosomal Protein S9

Flavonoids have been reported to inhibit tumor growth by causing cell cycle arrest. However, little is known about the direct targets of flavonoids in tumor growth inhibition. In the present study, we developed a novel method using magnetic FG beads to purify flavonoid-binding proteins, and identifi...

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Detalhes bibliográficos
Main Authors: Iizumi, Yosuke, Oishi, Masakatsu, Taniguchi, Tomoyuki, Goi, Wakana, Sowa, Yoshihiro, Sakai, Toshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756953/
https://ncbi.nlm.nih.gov/pubmed/24009741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073219
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