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Hypothalamic Programming of Systemic Aging Involving IKKβ/NF-κB and GnRH

Aging is a result of gradual and overall functional deteriorations across the body; however, it is unknown if an individual tissue works to primarily mediate aging progress and lifespan control. Here we found that the hypothalamus is important for the development of whole-body aging in mice, and the...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Guo, Li, Juxue, Purkayastha, Sudarshana, Tang, Yizhe, Zhang, Hai, Yin, Ye, Li, Bo, Liu, Gang, Cai, Dongsheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756938/
https://ncbi.nlm.nih.gov/pubmed/23636330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12143
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