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WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion

Wiskott-Aldrich syndrome protein and SCAR homologue (WASH) is an important regulator of vesicle trafficking. By generating actin on the surface of intracellular vesicles, WASH is able to directly regulate endosomal sorting and maturation. We report that, in Dictyostelium, WASH is also required for t...

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Main Authors: King, Jason S., Gueho, Aurélie, Hagedorn, Monica, Gopaldass, Navin, Leuba, Florence, Soldati, Thierry, Insall, Robert H.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756923/
https://ncbi.nlm.nih.gov/pubmed/23885127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-02-0092
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