Memantine in frontotemporal lobar degeneration: A multicenter, randomised, double-blind, placebo-controlled trial

BACKGROUND: Memantine has been used off-label to treat frontotemporal lobar degeneration (FTD). A previous 26 week open label study suggested a transient, modest benefit on neuropsychiatric symptoms as measured by the Neuropsychiatric Inventory (NPI). METHODS: We performed a randomized, parallel gro...

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Detalhes bibliográficos
Main Authors: Boxer, Adam L., Knopman, David S., Kaufer, Daniel I., Grossman, Murray, Onyike, Chiadi, Graf-Radford, Neill, Mendez, Mario, Kerwin, Diana, Lerner, Alan, Wu, Chuang-Kuo, Koestler, Mary, Shapira, Jill, Sullivan, Kathryn, Klepac, Kristen, Lipowski, Kristine, Ullah, Jerin, Fields, Scott, Kramer, Joel H., Merrilees, Jennifer, Neuhaus, John, Mesulam, M. Marsel, Miller, Bruce L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756890/
https://ncbi.nlm.nih.gov/pubmed/23290598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(12)70320-4
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