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Stimulation of mGluR5 in the Accumbens Shell Promotes Cocaine Seeking by Activating PKC Gamma

Recent studies indicate a critical role for metabotropic glutamate receptor 5 (mGluR5) in the reinstatement of cocaine seeking. However, the signal transduction pathways through which mGluR5s regulate cocaine seeking have not been identified. Here, we show that intra-accumbens shell administration o...

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Hlavní autoři: Schmidt, Heath D., Schassburger, Rachel L., Guercio, Leonardo A., Pierce, R. Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756760/
https://ncbi.nlm.nih.gov/pubmed/23986250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2284-13.2013
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