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A systematic analysis of the PARP protein family identifies new functions critical for cell physiology

The poly(ADP-ribose) polymerase (PARP) family of proteins use NAD(+) as their substrate to modify acceptor proteins with adenosine diphosphate-ribose (ADPr) modifications. The function of most PARPs under physiological conditions is unknown. Here, to better understand this protein family, we systema...

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Detalhes bibliográficos
Main Authors: Vyas, Sejal, Chesarone-Cataldo, Melissa, Todorova, Tanya, Huang, Yun-Han, Chang, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756671/
https://ncbi.nlm.nih.gov/pubmed/23917125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3240
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