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Role of PKCα Activation of Src, PI-3K/AKT, and ERK in EGF-Stimulated Proliferation of Rat and Human Conjunctival Goblet Cells

PURPOSE. To determine the order and components of the signaling pathway utilized by epidermal growth factor (EGF) to stimulate conjunctival goblet cell proliferation. METHODS. Goblet cells from rat bulbar and forniceal conjunctiva and human bulbar conjunctiva were grown in organ culture. Goblet cell...

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Detalhes bibliográficos
Main Authors: Li, Dayu, Shatos, Marie A., Hodges, Robin R., Dartt, Darlene A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756614/
https://ncbi.nlm.nih.gov/pubmed/23882690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12473
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