Three Mechanisms Assemble Central Nervous System Nodes of Ranvier

Rapid action potential propagation in myelinated axons requires Na(+) channel clustering at nodes of Ranvier. However, the mechanism of clustering at CNS nodes remains poorly understood. Here, we show that the assembly of nodes of Ranvier in the CNS involves three mechanisms: a glia-derived extracel...

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Main Authors: Susuki, Keiichiro, Chang, Kae-Jiun, Zollinger, Daniel R., Liu, Yanhong, Ogawa, Yasuhiro, Eshed-Eisenbach, Yael, Dours-Zimmermann, María T., Oses-Prieto, Juan A., Burlingame, Alma L., Seidenbecher, Constanze I., Zimmermann, Dieter R., Oohashi, Toshitaka, Peles, Elior, Rasband, Matthew N.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756512/
https://ncbi.nlm.nih.gov/pubmed/23664614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.005
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