Genetically determined ABCB5 functionality correlates with pigmentation phenotype and melanoma risk

ABCB5 is a multidrug resistance (MDR) member of the ATP-binding cassette (ABC) superfamily of active transporters and represents a marker for chemoresistant malignant melanoma-initiating cells. ABCB5 expression is closely linked to tumorigenicity and progression of diverse human malignancies, includ...

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Detalhes bibliográficos
Main Authors: Lin, Jennifer Y., Zhang, Mingfeng, Schatton, Tobias, Wilson, Brian J., Alloo, Allireza, Ma, Jie, Qureshi, Abrar A., Frank, Natasha Y., Han, Jiali, Frank, Markus H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756469/
https://ncbi.nlm.nih.gov/pubmed/23770371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.06.006
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