A novel in vivo regulatory role of P-glycoprotein in alloimmunity

P-glycoprotein (P-gp) is required for adaptive immunity through defined functions in T cell activation and antigen presenting cell (APC) maturation. The potential role of P-gp as an in vivo regulator of alloimmunity is currently unknown. Here we show that P-gp blockade prolongs graft survival in a m...

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Detalhes bibliográficos
Main Authors: Izawa, Atsushi, Schatton, Tobias, Frank, Natasha Y., Ueno, Takuya, Yamaura, Kazuhiro, Pendse, Shona S., Margaryan, Armen, Grimm, Martin, Gasser, Martin, Waaga-Gasser, Ana Maria, Sayegh, Mohamed H., Frank, Markus H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756468/
https://ncbi.nlm.nih.gov/pubmed/20230790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.03.040
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