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microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus

microRNAs regulate the expression of over 60% of protein coding genes by targeting their mRNAs to AGO2-containing complexes in the cytoplasm and promoting their translational inhibition and/or degradation. There is little evidence so far for microRNA-mediated regulation of other classes of non-codin...

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Bibliografiske detaljer
Main Authors: Leucci, Eleonora, Patella, Francesca, Waage, Johannes, Holmstrøm, Kim, Lindow, Morten, Porse, Bo, Kauppinen, Sakari, Lund, Anders H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756333/
https://ncbi.nlm.nih.gov/pubmed/23985560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02535
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