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Matrix Composition Regulates Three-Dimensional Network Formation by Endothelial Cells and Mesenchymal Stem Cells in Collagen/Fibrin Materials

Co-cultures of endothelial cells (EC) and mesenchymal stem cells (MSC) in three-dimensional (3D) protein hydrogels can be used to recapitulate aspects of vasculogenesis in vitro. MSC provide paracrine signals that stimulate EC to form vessel-like structures, which mature as the MSC transition to the...

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Autors principals: Rao, Rameshwar R., Peterson, Alexis W., Ceccarelli, Jacob, Putnam, Andrew J., Stegemann, Jan P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756314/
https://ncbi.nlm.nih.gov/pubmed/22382584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9257-1
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