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Tamoxifen and the Risk of Ovarian Cancer in BRCA1 Mutation Carriers

OBJECTIVE: BRCA1 mutation carriers have a high rate of both breast and ovarian cancer. Tamoxifen is a selective estrogen receptor modulator (SERM), which is used for the treatment of primary breast cancer and for the prevention of contralateral breast cancer. Our objective is to assess if tamoxifen...

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Hlavní autoři: Vicus, Danielle, Rosen, Barry, Lubinski, Jan, Domchek, Susan, Kauff, Noah D., Lynch, Henry T., Isaacs, Claudine, Tung, Nadine, Sun, Ping, Narod, Steven A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756313/
https://ncbi.nlm.nih.gov/pubmed/19577280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2009.06.012
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