Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus

Random mutagenesis combined with phenotypic screening using carefully crafted functional tests has successfully led to the discovery of genes that are essential for a number of functions. This approach does not require prior knowledge of the identity of the genes that are involved and is a way to as...

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Autori principali: Pinto, Lawrence H., Vitaterna, Martha Hotz, Siepka, Sanda M., Shimomura, Kazuhiro, Lumayag, Stephen, Baker, Matthew, Fenner, Deborah, Mullins, Robert F., Sheffield, Val C., Stone, Edwin M., Heffron, Edward, Takahashi, Joseph S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756145/
https://ncbi.nlm.nih.gov/pubmed/15536001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2004.07.025
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