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New insights on the pathogenesis of biliary cirrhosis provided by studies in FXR knockout mice
The nuclear bile acid receptor, farnesoid X receptor (FXR), may play a pivotal role in liver fibrosis. We tested the impact of genetic FXR ablation in four different mouse models. Hepatic fibrosis was induced in wild-type and FXR knock-out mice (FXR((−/−))) by CCl(4) intoxication, 3,5-diethoxycarbon...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3756144/ https://ncbi.nlm.nih.gov/pubmed/21672564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2011.04.013 |
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