Altered DNA Methylation Patterns of the H19 Differentially Methylated Region and the DAZL Gene Promoter Are Associated with Defective Human Sperm

DNA methylation disturbance is associated with defective human sperm. However, oligozoospermia (OZ) and asthenozoospermia (AZ) usually present together, and the relationship between the single-phenotype defects in human sperm and DNA methylation is poorly understood. In this study, 20 infertile OZ p...

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Detalhes bibliográficos
Main Authors: Li, Bo, Li, Jian-bo, Xiao, Xi-feng, Ma, Ye-fei, Wang, Jun, Liang, Xin-xin, Zhao, Hong-xi, Jiang, Feng, Yao, Yuan-qing, Wang, Xiao-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756053/
https://ncbi.nlm.nih.gov/pubmed/24015185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071215
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