Immunization of Mastomys coucha with Brugia malayi Recombinant Trehalose-6-Phosphate Phosphatase Results in Significant Protection against Homologous Challenge Infection

Development of a vaccine to prevent or reduce parasite development in lymphatic filariasis would be a complementary approach to existing chemotherapeutic tools. Trehalose-6-phosphate phosphatase of Brugia malayi (Bm-TPP) represents an attractive vaccine target due to its absence in mammals, prevalen...

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Bibliographic Details
Main Authors: Kushwaha, Susheela, Singh, Prashant Kumar, Rana, Ajay Kumar, Misra-Bhattacharya, Shailja
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755969/
https://ncbi.nlm.nih.gov/pubmed/24015262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072585
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