Perivascular Adipose Tissue Potentiates Contraction of Coronary Vascular Smooth Muscle: Influence of Obesity

BACKGROUND: This investigation examined the mechanisms by which coronary perivascular adipose tissue (PVAT)-derived factors influence vasomotor tone and the PVAT proteome in lean vs. obese swine. METHODS AND RESULTS: Coronary arteries from Ossabaw swine were isolated for isometric tension studies. W...

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Hauptverfasser: Owen, Meredith Kohr, Witzmann, Frank A., McKenney, Mikaela L., Lai, Xianyin, Berwick, Zachary C., Moberly, Steven P., Alloosh, Mouhamad, Sturek, Michael, Tune, Johnathan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755741/
https://ncbi.nlm.nih.gov/pubmed/23685742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.001238
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