Antagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates

It remains unclear whether basophils and mast cells are derived from a common progenitor. Furthermore, how basophil versus mast cell fate is specified has not been investigated. Here, we have identified a population of granulocyte-macrophage progenitors (GMPs), which were highly enriched in the capa...

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Detalhes bibliográficos
Main Authors: Qi, Xiaopeng, Hong, Jessie, Chaves, Lee, Zhuang, Yonghua, Chen, Yuhong, Wang, Demin, Chabon, Jacob, Graham, Brian, Ohmori, Keitaro, Li, Yapeng, Huang, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755602/
https://ncbi.nlm.nih.gov/pubmed/23871207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.06.012
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