Changes in molecular biology of chronic myeloid leukemia in tyrosine kinase inhibitor era

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disease characterized by a reciprocal translocation between long arms of chromosomes 9 and 22 t(9;22) that generates the BCR-ABL fusion gene. If left untreated, newly diagnosed chronic phase CML patients finally progress to accelerated an...

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Bibliographic Details
Main Authors: Comert, Melda, Baran, Yusuf, Saydam, Guray
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2013
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755521/
https://ncbi.nlm.nih.gov/pubmed/23997982
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