Genetic variation in the upstream region of ERG and prostate cancer

OBJECTIVE: A considerable fraction of prostate cancers harbor a gene fusion between the androgen-regulated TMPRSS2 and ERG, one of the most frequently over-expressed proto-oncogenes in prostate cancer. Here, we investigated if inherited genetic variation upstream of ERG alters prostate cancer risk a...

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Main Authors: Lindström, Sara, Adami, Hans-Olov, Bälter, Katarina, Xu, Jianfeng, Zheng, S. Lilly, Sun, Jielin, Stattin, Pär, Grönberg, Henrik, Wiklund, Fredrik
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755494/
https://ncbi.nlm.nih.gov/pubmed/19205910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-009-9305-3
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