Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models

Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) binding agent, has proven to be an effective monotherapy for metastatic melanoma and has shown antitumor activity in trials when administered with other therapeutic agents. We hypothesized that the combination of ipilimumab with chemotherapeuti...

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Detaylı Bibliyografya
Asıl Yazarlar: Jure-Kunkel, Maria, Masters, Gregg, Girit, Emel, Dito, Gennaro, Lee, Francis, Hunt, John T., Humphrey, Rachel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755230/
https://ncbi.nlm.nih.gov/pubmed/23873089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1451-5
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