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In Vitro–In Vivo Correlation of Efavirenz Tablets Using GastroPlus®

The aim of the present work was to use GastroPlus™ software for the prediction of pharmacokinetic profiles and in vitro–in vivo correlation (IVIVC) as tools to optimize the development of new generic medications. GastroPlus™ was used to simulate the gastrointestinal compartment and was based on the...

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Main Authors: Honório, Thiago da Silva, Pinto, Eduardo Costa, Rocha, Helvécio Vinicius A., Esteves, Valeria Sant’Anna Dantas, dos Santos, Tereza Cristina, Castro, Helena Carla Rangel, Rodrigues, Carlos Rangel, de Sousa, Valeria Pereira, Cabral, Lucio Mendes
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755163/
https://ncbi.nlm.nih.gov/pubmed/23943401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0016-4
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