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Influence of Critical Parameters of Nanosuspension Formulation on the Permeability of a Poorly Soluble Drug through the Skin—A Case Study

In transdermal drug delivery systems, it is always a challenge to achieve stable and prolonged high permeation rates across the skin since the concentrations of the drug dissolved in the matrix have to be high in order to maintain zero order release kinetics. Several attempts have been reported to i...

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Detalhes bibliográficos
Main Authors: Ghosh, Indrajit, Michniak-Kohn, Bozena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755145/
https://ncbi.nlm.nih.gov/pubmed/23824877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9995-4
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