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Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists

A series of 5-alkylsulfamoyl benzimidazole derivatives have been designed and synthesized as novel angiotensin II (Ang II) receptor antagonists. The compounds have been evaluated for in vitro Ang II antagonism and for in vivo antihypertensive activity on isolated rat aortic ring and desoxycortisone...

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Bibliografski detalji
Glavni autori: Kaur, Navneet, Kaur, Amardeep, Bansal, Yogita, Shah, Dhvanit I., Bansal, Gulshan, Singh, Manjeet
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755122/
https://ncbi.nlm.nih.gov/pubmed/19013821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.056
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