Chitin-Binding Domains of Escherichia coli chiA Mediate Interactions With Intestinal Epithelial Cells in Mice with Colitis

BACKGROUND & AIMS: Inducible chitinase 3-like-1 (CHI3L1) is expressed by intestinal epithelial cells (IECs) and adheres to bacteria under conditions of inflammation. We performed a structure–function analysis of the chitin-binding domains (CBDs) encoded by the chiA gene, which mediates the patho...

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Hlavní autoři: Low, Daren, Tran, Hoa T., Lee, In-Ah, Dreux, Nicolas, Kamba, Alan, Reinecker, Hans-Christian, Darfeuille-Michaud, Arlette, Barnich, Nicolas, Mizoguchi, Emiko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755095/
https://ncbi.nlm.nih.gov/pubmed/23684751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.05.017
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