Fludarabine/2 Gy TBI is Superior to 2 Gy TBI as Conditioning for HLA-Matched Related HCT: A Phase III Randomized Trial

The risk/benefit of adding fludarabine to a 2 Gy total body irradiation nonmyeloablative regimen is unknown. For this reason we conducted a prospective randomized trial comparing 2 Gy TBI alone or in combination with 90mg/m(2) fludarabine (FLU/TBI) before transplantation of peripheral blood stem cel...

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Main Authors: Kornblit, Brian, Maloney, David G., Storb, Rainer, Storek, Jan, Hari, Parameswaran, Vucinic, Vladan, Maziarz, Richard T., Chauncey, Thomas R., Pulsipher, Michael A., Bruno, Benedetto, Petersen, Finn B., Bethge, Wolfgang A., Hübel, Kai, Bouvier, Michelle E., Fukuda, Takahiro, Storer, Barry E., Sandmaier, Brenda M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755028/
https://ncbi.nlm.nih.gov/pubmed/23769990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.06.002
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