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Examination of Artificial MiRNA Mimics with Centered–Site Complementarity for Gene Targeting

BACKGROUND: MiRNA primarily acts to repress gene expression at the post-transcriptional level through imperfect complementarity of its 5′ region to the “seed site” in the 3′ untranslated region of target mRNAs, with its “3′–supplementary site” and “center site” also playing important roles under cer...

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Detalhes bibliográficos
Main Authors: Zhang, Shu-Guang, Liu, Chun-Yan, Li, Li, Sun, Tong-Wen, Luo, Yong-Gang, Yun, Wen-Jing, Zhang, Jin-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754971/
https://ncbi.nlm.nih.gov/pubmed/24013456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072062
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