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Mycoplasma fermentans Inhibits the Activity of Cellular DNA Topoisomerase I by Activation of PARP1 and Alters the Efficacy of Its Anti-Cancer Inhibitor

To understand the effects of the interaction between Mycoplasma and cells on the host cellular function, it is important to elucidate the influences of infection of cells with Mycoplasma on nuclear enzymes such as DNA Topoisomerase type I (Topo I). Human Topo I participates in DNA transaction proces...

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Detalhes bibliográficos
Main Authors: Afriat, Reuven, Horowitz, Shulamith, Priel, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754970/
https://ncbi.nlm.nih.gov/pubmed/24013388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072377
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