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The CK2 Kinase Stabilizes CLOCK and Represses Its Activity in the Drosophila Circadian Oscillator

Phosphorylation is a pivotal regulatory mechanism for protein stability and activity in circadian clocks regardless of their evolutionary origin. It determines the speed and strength of molecular oscillations by acting on transcriptional activators and their repressors, which form negative feedback...

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Detalhes bibliográficos
Main Authors: Szabó, Áron, Papin, Christian, Zorn, Daniela, Ponien, Prishila, Weber, Frank, Raabe, Thomas, Rouyer, François
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754892/
https://ncbi.nlm.nih.gov/pubmed/24013921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001645
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