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Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization()
Oxygen homeostasis represents an essential organizing principle of metazoan evolution and biology. Hypoxia-inducible factor 1 (HIF-1) is a master regulator of transcriptional responses to changes in O(2) concentration. HIF-1 is a heterodimer of HIF-1α and HIF-1β subunits. O(2)-dependent degradation...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754800/ https://ncbi.nlm.nih.gov/pubmed/17965024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705015200 |
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