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Structural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c–I-E(k)

T cells specific for the cytochrome c Ag are widely used to investigate many aspects of TCR specificity and interactions with peptide-MHC, but structural information has long been elusive. In this study, we present structures for the well-studied 2B4 TCR, as well as a naturally occurring variant of...

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Detalhes bibliográficos
Main Authors: Newell, Evan W., Ely, Lauren K., Kruse, Andrew C., Reay, Philip A., Rodriguez, Stephanie N., Lin, Aaron E., Kuhns, Michael S., Garcia, K. Christopher, Davis, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754796/
https://ncbi.nlm.nih.gov/pubmed/21490152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100197
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