Dextran-b-poly(L-histidine) copolymer nanoparticles for ph-responsive drug delivery to tumor cells

PURPOSE: Nanoparticles based on stimuli-sensitive drug delivery have been extensively investigated for tumor targeting. Among them, pH-responsive drug targeting using pH-sensitive polymers has attracted attention because solid tumors have an acidic environment. A dextran-b-poly(L-histidine) (DexPHS)...

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Autores principales: Hwang, Jong-ho, Choi, Cheol Woong, Kim, Hyung-Wook, Kim, Do Hyung, Kwak, Tae Won, Lee, Hye Myeong, Kim, Cy hyun, Chung, Chung Wook, Jeong, Young-II, Kang, Dae Hwan
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754766/
https://ncbi.nlm.nih.gov/pubmed/23986636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S49459
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