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Caspase Activation as a Versatile Assay Platform for Detection of Cytotoxic Bacterial Toxins

Pathogenic bacteria produce several virulence factors that help them establish infection in permissive hosts. Bacterial toxins are a major class of virulence factors and hence are attractive therapeutic targets for vaccine development. Here, we describe the development of a rapid, sensitive, and hig...

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Detalhes bibliográficos
Main Authors: Payne, Angela M., Zorman, Julie, Horton, Melanie, Dubey, Sheri, ter Meulen, Jan, Vora, Kalpit A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754665/
https://ncbi.nlm.nih.gov/pubmed/23824772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01161-13
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