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Diagnostic Implications of Inconsistent Results Obtained with the Xpert MTB/Rif Assay in Detection of Mycobacterium tuberculosis Isolates with an rpoB Mutation Associated with Low-Level Rifampin Resistance

Xpert-MTB/Rif is one of the most frequently used molecular screening tests for multidrug-resistant tuberculosis worldwide. We report false-negative assay results in the presence of rpoB Leu533Pro, which is associated with low-level phenotypic rifampin resistance. Accurate and timely confirmation of...

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Detalhes bibliográficos
Main Authors: Somoskovi, Akos, Deggim, Vanessa, Ciardo, Diana, Bloemberg, Guido V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754655/
https://ncbi.nlm.nih.gov/pubmed/23850949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01377-13
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