Pharmacogenomics of Cytauxzoon felis Cytochrome b: Implications for Atovaquone and Azithromycin Therapy in Domestic Cats with Cytauxzoonosis

Cytauxzoon felis, an emerging virulent protozoan parasite that infects domestic cats, is treated with atovaquone and azithromycin (A&A). Atovaquone targets parasite cytochrome b. We characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonosis and found a cytb genotype that was...

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Autors principals: Schreeg, Megan E., Marr, Henry S., Tarigo, Jaime, Cohn, Leah A., Levy, Michael G., Birkenheuer, Adam J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Clinical Veterinary Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754644/
https://ncbi.nlm.nih.gov/pubmed/23784135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01407-13
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