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An Inactivated, Adjuvanted Whole Virion Clade 2.2 H5N1 (A/Chicken/Astana/6/05) Influenza Vaccine Is Safe and Immunogenic in a Single Dose in Humans

In this study, we assessed in humans the immunogenicity and safety of one dose (7.5 or 15 μg of hemagglutinin [HA]) of a whole-virion inactivated prepandemic influenza vaccine adjuvanted with aluminum hydroxide. The vaccine strain was made by reverse genetics from the highly pathogenic avian A/Chick...

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Detalhes bibliográficos
Main Authors: Sansyzbay, Abylay R., Erofeeva, Marianna K., Khairullin, Berik M., Sandybayev, Nurlan T., Kydyrbayev, Zhailaubay K., Mamadaliyev, Seidigapbar M., Kassenov, Markhabat M., Sergeeva, Maria V., Romanova, Julia R., Krivitskaya, Vera Z., Kiselev, Oleg I., Stukova, Marina A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754517/
https://ncbi.nlm.nih.gov/pubmed/23803900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00096-13
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