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Development of a Highly Sensitive Bioluminescent Enzyme Immunoassay for Hepatitis B Virus Surface Antigen Capable of Detecting Divergent Mutants

Hepatitis B virus (HBV) infections are sometimes overlooked when using commercial kits to measure hepatitis B virus surface antigen (HBsAg) due to their low sensitivities and reactivities to mutant strains of various genotypes. We developed an ultrasensitive bioluminescent enzyme immunoassay (BLEIA)...

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Main Authors: Minekawa, Takayuki, Takehara, Shizuka, Takahashi, Masaharu, Okamoto, Hiroaki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754505/
https://ncbi.nlm.nih.gov/pubmed/23761660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00186-13
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