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Reducing the Level of Undecaprenyl Pyrophosphate Synthase Has Complex Effects on Susceptibility to Cell Wall Antibiotics
Undecaprenyl pyrophosphate synthase (UppS) catalyzes the formation of the C(55) lipid carrier (UPP) that is essential for bacterial peptidoglycan biosynthesis. We selected here a vancomycin (VAN)-resistant derivative of Bacillus subtilis W168 that contains a single-point mutation in the ribosome-bin...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754353/ https://ncbi.nlm.nih.gov/pubmed/23796923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00794-13 |
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